ERVW-1 Break Apart FISH Probe
Empire Genomics’ ERVW-1 Break Apart FISH Probe is designed to flank the ERVW-1 gene and is typically used for detecting ERVW-1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
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ERVW-1BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL | ||
ERVW-1BA-20-AQOR | 20 (40 μL) | 200 μL | ||
ERVW-1BA-20-GOGR | 20 (40 μL) | 200 μL | ||
ERVW-1BA-20-GORE | 20 (40 μL) | 200 μL | ||
ERVW-1BA-20-GRGO | 20 (40 μL) | 200 μL | ||
ERVW-1BA-20-GRRE | 20 (40 μL) | 200 μL | ||
ERVW-1BA-20-ORGR | 20 (40 μL) | 200 μL | ||
ERVW-1BA-20-REGO | 20 (40 μL) | 200 μL | ||
ERVW-1BA-20-REGR | 20 (40 μL) | 200 μL |
Gene Summary
Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of an HERV provirus on chromosome 7 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. The protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Mar 2010]
Gene Details
Gene Symbol: ERVW-1
Gene Name: Endogenous Retrovirus Group W Member 1, Envelope
Chromosome: CHR7: 92477914-92468379
Locus: 7q21.2
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ERVW-1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ERVW-1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping