ERVW-1 FISH Probe
The ERVW-1 FISH probe is designed to hybridize to the ERVW-1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ERVW-1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ERVW-1-20-RE | 20 (40 μL) | 200 μL |  |
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| ERVW-1-20-GO | 20 (40 μL) | 200 μL |  |
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| ERVW-1-20-GR | 20 (40 μL) | 200 μL |  |
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| ERVW-1-20-AQ | 20 (40 μL) | 200 μL |  |
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| ERVW-1-20-DIG | 20 (40 μL) | 200 μL |  |
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| ERVW-1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of an HERV provirus on chromosome 7 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. The protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Mar 2010]
Gene Details
Gene Symbol: ERVW-1
Gene Name: Endogenous Retrovirus Group W Member 1, Envelope
Chromosome: CHR7: 92477914-92468379
Locus: 7q21.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ERVW-1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ERVW-1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping