ERN1 FISH Probe
The ERN1 FISH probe is designed to hybridize to the ERN1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ERN1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ERN1-20-RE | 20 (40 μL) | 200 μL |  |
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| ERN1-20-GO | 20 (40 μL) | 200 μL |  |
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| ERN1-20-GR | 20 (40 μL) | 200 μL |  |
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| ERN1-20-AQ | 20 (40 μL) | 200 μL |  |
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| ERN1-20-DIG | 20 (40 μL) | 200 μL |  |
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| ERN1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes the transmembrane protein kinase inositol-requiring enzyme 1. The encoded protein contains two functional catalytic domains, a serine/threonine-protein kinase domain and an endoribonuclease domain. This protein functions as a sensor of unfolded proteins in the endoplasmic reticulum (ER) and triggers an intracellular signaling pathway termed the unfolded protein response (UPR). The UPR is an ER stress response that is conserved from yeast to mammals and activates genes involved in degrading misfolded proteins, regulating protein synthesis and activating molecular chaperones. This protein specifically mediates the splicing and activation of the stress response transcription factor X-box binding protein 1. [provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: ERN1
Gene Name: Endoplasmic Reticulum To Nucleus Signaling 1
Chromosome: CHR17: 62120389-62207502
Locus: 17q23.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ERN1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ERN1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping