ERK FISH Probe
The ERK FISH probe is designed to hybridize to the ERK gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MAPK1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MAPK1-20-RE | 20 (40 μL) | 200 μL |  |
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| MAPK1-20-GO | 20 (40 μL) | 200 μL |  |
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| MAPK1-20-GR | 20 (40 μL) | 200 μL |  |
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| MAPK1-20-AQ | 20 (40 μL) | 200 μL |  |
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| MAPK1-20-DIG | 20 (40 μL) | 200 μL |  |
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| MAPK1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jan 2014]
Gene Details
Gene Symbol: MAPK1
Gene Name: Mitogen-activated Protein Kinase 1
Chromosome: CHR22: 22113946-22221970
Locus: 22q11.22
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ERK FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MAPK1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping