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ERK FISH Probe

The ERK FISH probe is designed to hybridize to the ERK gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
MAPK1-20-OR  (Standard Design) 20 (40 μL) 200 μL
MAPK1-20-RE 20 (40 μL) 200 μL
MAPK1-20-GO 20 (40 μL) 200 μL
MAPK1-20-GR 20 (40 μL) 200 μL
MAPK1-20-AQ 20 (40 μL) 200 μL
MAPK1-20-DIG 20 (40 μL) 200 μL
MAPK1-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jan 2014]

Gene Details

Gene Symbol: MAPK1

Gene Name: Mitogen-activated Protein Kinase 1

Chromosome: CHR22: 22113946-22221970

Locus: 22q11.22

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: ERK FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: MAPK1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping