ERCC6L FISH Probe
The ERCC6L FISH probe is designed to hybridize to the ERCC6L gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ERCC6L-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ERCC6L-20-RE | 20 (40 μL) | 200 μL |  |
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| ERCC6L-20-GO | 20 (40 μL) | 200 μL |  |
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| ERCC6L-20-GR | 20 (40 μL) | 200 μL |  |
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| ERCC6L-20-AQ | 20 (40 μL) | 200 μL |  |
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| ERCC6L-20-DIG | 20 (40 μL) | 200 μL |  |
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| ERCC6L-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the SWItch/Sucrose Non-Fermentable (SWI/SNF2) family of proteins, and contains a SNF2-like ATPase domain and a PICH family domain. One distinguishing feature of this SWI/SNF protein family member is that during interphase, the protein is excluded from the nucleus, and only associates with chromatin after the nuclear envelope has broken down. This protein is a DNA translocase that is thought to bind double-stranded DNA that is exposed to stretching forces, such as those exerted by the mitotic spindle. This protein associates with ribosomal DNA and ultra-fine DNA bridges (UFBs), fine structures that connect sister chromatids during anaphase at some sites such as fragile sites, telomeres and centromeres. This gene is required for the faithful segregation of sister chromatids during mitosis, and the ATPase activity of this protein required for the resolution of UFBs before cytokinesis. [provided by RefSeq, May 2017]
Gene Details
Gene Symbol: ERCC6L
Gene Name: ERCC Excision Repair 6 Like, Spindle Assembly Checkpoint Helicase
Chromosome: CHRX: 71424506-71458858
Locus: Xq13.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ERCC6L FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ERCC6L-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping