ERCC5 FISH Probe
The ERCC5 FISH probe is designed to hybridize to the ERCC5 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ERCC5-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| ERCC5-20-RE | 20 (40 μL) | 200 μL |  |
|
| ERCC5-20-GO | 20 (40 μL) | 200 μL |  |
|
| ERCC5-20-GR | 20 (40 μL) | 200 μL |  |
|
| ERCC5-20-AQ | 20 (40 μL) | 200 μL |  |
|
| ERCC5-20-DIG | 20 (40 μL) | 200 μL |  |
|
| ERCC5-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage. The protein may also function in other cellular processes, including RNA polymerase II transcription, and transcription-coupled DNA repair. Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G), which is also referred to as xeroderma pigmentosum VII (XP7), a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure. Some patients also develop Cockayne syndrome, which is characterized by severe growth defects, cognitive disability, and cachexia. Read-through transcription exists between this gene and the neighboring upstream BIVM (basic, immunoglobulin-like variable motif containing) gene. [provided by RefSeq, Feb 2011]
Gene Details
Gene Symbol: ERCC5
Gene Name: ERCC Excision Repair 5, Endonuclease
Chromosome: CHR13: 103498190-103528351
Locus: 13q33.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: ERCC5 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ERCC5-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping