EPO FISH Probe
The EPO FISH probe is designed to hybridize to the EPO gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| EPO-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| EPO-20-RE | 20 (40 μL) | 200 μL |  |
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| EPO-20-GO | 20 (40 μL) | 200 μL |  |
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| EPO-20-GR | 20 (40 μL) | 200 μL |  |
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| EPO-20-AQ | 20 (40 μL) | 200 μL |  |
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| EPO-20-DIG | 20 (40 μL) | 200 μL |  |
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| EPO-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The encoded protein is mainly synthesized in the kidney, secreted into the blood plasma, and binds to the erythropoietin receptor to promote red blood cell production, or erythropoiesis, in the bone marrow. Expression of this gene is upregulated under hypoxic conditions, in turn leading to increased erythropoiesis and enhanced oxygen-carrying capacity of the blood. Expression of this gene has also been observed in brain and in the eye, and elevated expression levels have been observed in diabetic retinopathy and ocular hypertension. Recombinant forms of the encoded protein exhibit neuroprotective activity against a variety of potential brain injuries, as well as antiapoptotic functions in several tissue types, and have been used in the treatment of anemia and to enhance the efficacy of cancer therapies. [provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: EPO
Gene Name: Erythropoietin
Chromosome: CHR7: 100318422-100321323
Locus: 7q22.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: EPO FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: EPO-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping