EPM2A FISH Probe
The EPM2A FISH probe is designed to hybridize to the EPM2A gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| EPM2A-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| EPM2A-20-RE | 20 (40 μL) | 200 μL |  |
|
| EPM2A-20-GO | 20 (40 μL) | 200 μL |  |
|
| EPM2A-20-GR | 20 (40 μL) | 200 μL |  |
|
| EPM2A-20-AQ | 20 (40 μL) | 200 μL |  |
|
| EPM2A-20-DIG | 20 (40 μL) | 200 μL |  |
|
| EPM2A-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a dual-specificity phosphatase and may be involved in the regulation of glycogen metabolism. The protein acts on complex carbohydrates to prevent glycogen hyperphosphorylation, thus avoiding the formation of insoluble aggregates. Loss-of-function mutations in this gene have been associated with Lafora disease, a rare, adult-onset recessive neurodegenerative disease, which results in myoclonus epilepsy and usually results in death several years after the onset of symptoms. The disease is characterized by the accumulation of insoluble particles called Lafora bodies, which are derived from glycogen. [provided by RefSeq, Jan 2018]
Gene Details
Gene Symbol: EPM2A
Gene Name: EPM2A, Laforin Glucan Phosphatase
Chromosome: CHR6: 145946439-146056991
Locus: 6q24.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: EPM2A FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: EPM2A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping