EPHB2 FISH Probe
The EPHB2 FISH probe is designed to hybridize to the EPHB2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| EPHB2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| EPHB2-20-RE | 20 (40 μL) | 200 μL |  |
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| EPHB2-20-GO | 20 (40 μL) | 200 μL |  |
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| EPHB2-20-GR | 20 (40 μL) | 200 μL |  |
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| EPHB2-20-AQ | 20 (40 μL) | 200 μL |  |
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| EPHB2-20-DIG | 20 (40 μL) | 200 μL |  |
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| EPHB2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility, division, and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade, resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]
Gene Details
Gene Symbol: EPHB2
Gene Name: EPH Receptor B2
Chromosome: CHR1: 23037330-23241823
Locus: 1p36.12
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: EPHB2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: EPHB2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping