EP300 FISH Probe
The EP300 FISH probe is designed to hybridize to the EP300 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| EP300-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| EP300-20-RE | 20 (40 μL) | 200 μL |  |
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| EP300-20-GO | 20 (40 μL) | 200 μL |  |
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| EP300-20-GR | 20 (40 μL) | 200 μL |  |
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| EP300-20-AQ | 20 (40 μL) | 200 μL |  |
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| EP300-20-DIG | 20 (40 μL) | 200 μL |  |
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| EP300-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: EP300
Gene Name: E1A Binding Protein P300
Chromosome: CHR22: 41488613-41576081
Locus: 22q13.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: EP300 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: EP300-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping