END FISH Probe
The END FISH probe is designed to hybridize to the END gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ENG-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ENG-20-RE | 20 (40 μL) | 200 μL |  |
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| ENG-20-GO | 20 (40 μL) | 200 μL |  |
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| ENG-20-GR | 20 (40 μL) | 200 μL |  |
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| ENG-20-AQ | 20 (40 μL) | 200 μL |  |
|
| ENG-20-DIG | 20 (40 μL) | 200 μL |  |
|
| ENG-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]
Gene Details
Gene Symbol: ENG
Gene Name: Endoglin
Chromosome: CHR9: 130577290-130617047
Locus: 9q34.11
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: END FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ENG-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping