EMS1 FISH Probe
The EMS1 FISH probe is designed to hybridize to the EMS1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CTTN-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CTTN-20-RE | 20 (40 μL) | 200 μL |  |
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| CTTN-20-GO | 20 (40 μL) | 200 μL |  |
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| CTTN-20-GR | 20 (40 μL) | 200 μL |  |
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| CTTN-20-AQ | 20 (40 μL) | 200 μL |  |
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| CTTN-20-DIG | 20 (40 μL) | 200 μL |  |
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| CTTN-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq, May 2010]
Gene Details
Gene Symbol: CTTN
Gene Name: Cortactin
Chromosome: CHR11: 70244611-70282690
Locus: 11q13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: EMS1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CTTN-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping