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ELOB Break Apart FISH Probe

Empire Genomics’ ELOB Break Apart FISH Probe is designed to flank the ELOB gene and is typically used for detecting ELOB rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ELOBBA-20-GROR  (Standard Design) 20 (40 μL) 200 μL
ELOBBA-20-AQOR 20 (40 μL) 200 μL
ELOBBA-20-GOGR 20 (40 μL) 200 μL
ELOBBA-20-GORE 20 (40 μL) 200 μL
ELOBBA-20-GRGO 20 (40 μL) 200 μL
ELOBBA-20-GRRE 20 (40 μL) 200 μL
ELOBBA-20-ORGR 20 (40 μL) 200 μL
ELOBBA-20-REGO 20 (40 μL) 200 μL
ELOBBA-20-REGR 20 (40 μL) 200 μL

Gene Summary

This gene encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. Pseudogenes have been identified on chromosomes 11 and 13. [provided by RefSeq, Aug 2008]

Gene Details

Gene Symbol: ELOB

Gene Name: Elongin B

Chromosome: CHR16: 2777295-2771413

Locus: 16p13.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: ELOB FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: ELOB-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping