ELN Break Apart FISH Probe
Empire Genomics’ ELN Break Apart FISH Probe is designed to flank the ELN gene and is typically used for detecting ELN rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ELNBA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ELNBA-20-AQOR | 20 (40 μL) | 200 μL |
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| ELNBA-20-GOGR | 20 (40 μL) | 200 μL |
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| ELNBA-20-GORE | 20 (40 μL) | 200 μL |
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| ELNBA-20-GRGO | 20 (40 μL) | 200 μL |
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| ELNBA-20-GROR | 20 (40 μL) | 200 μL |
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| ELNBA-20-GRRE | 20 (40 μL) | 200 μL |
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| ELNBA-20-REGO | 20 (40 μL) | 200 μL |
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| ELNBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a protein that is one of the two components of elastic fibers. Elastic fibers comprise part of the extracellular matrix and confer elasticity to organs and tissues including the heart, skin, lungs, ligaments, and blood vessels. The encoded protein is rich in hydrophobic amino acids such as glycine and proline, which form mobile hydrophobic regions bounded by crosslinks between lysine residues. Degradation products of the encoded protein, known as elastin-derived peptides or elastokines, bind the elastin receptor complex and other receptors and stimulate migration and proliferation of monocytes and skin fibroblasts. Elastokines can also contribute to cancer progression. Deletions and mutations in this gene are associated with supravalvular aortic stenosis (SVAS) and autosomal dominant cutis laxa. [provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: ELN
Gene Name: Elastin
Chromosome: CHR7: 73442426-73484236
Locus: 7q11.23
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ELN FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ELN-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping