EIF4G2 Break Apart FISH Probe
Empire Genomics’ EIF4G2 Break Apart FISH Probe is designed to flank the EIF4G2 gene and is typically used for detecting EIF4G2 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| EIF4G2BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| EIF4G2BA-20-AQOR | 20 (40 μL) | 200 μL |
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| EIF4G2BA-20-GOGR | 20 (40 μL) | 200 μL |
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| EIF4G2BA-20-GORE | 20 (40 μL) | 200 μL |
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| EIF4G2BA-20-GRGO | 20 (40 μL) | 200 μL |
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| EIF4G2BA-20-GRRE | 20 (40 μL) | 200 μL |
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| EIF4G2BA-20-ORGR | 20 (40 μL) | 200 μL |
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| EIF4G2BA-20-REGO | 20 (40 μL) | 200 μL |
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| EIF4G2BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: EIF4G2
Gene Name: Eukaryotic Translation Initiation Factor 4 Gamma 2
Chromosome: CHR11: 10818592-10830582
Locus: 11p15.4
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: EIF4G2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: EIF4G2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping