EIF4F FISH Probe
The EIF4F FISH probe is designed to hybridize to the EIF4F gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| EIF4G1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| EIF4G1-20-RE | 20 (40 μL) | 200 μL |  |
|
| EIF4G1-20-GO | 20 (40 μL) | 200 μL |  |
|
| EIF4G1-20-GR | 20 (40 μL) | 200 μL |  |
|
| EIF4G1-20-AQ | 20 (40 μL) | 200 μL |  |
|
| EIF4G1-20-DIG | 20 (40 μL) | 200 μL |  |
|
| EIF4G1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq, Aug 2010]
Gene Details
Gene Symbol: EIF4G1
Gene Name: Eukaryotic Translation Initiation Factor 4 Gamma 1
Chromosome: CHR3: 184032282-184053146
Locus: 3q27.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: EIF4F FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: EIF4G1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping