EIF2A Break Apart FISH Probe
Empire Genomics’ EIF2A Break Apart FISH Probe is designed to flank the EIF2A gene and is typically used for detecting EIF2A rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| EIF2ABA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| EIF2ABA-20-AQOR | 20 (40 μL) | 200 μL |
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| EIF2ABA-20-GOGR | 20 (40 μL) | 200 μL |
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| EIF2ABA-20-GORE | 20 (40 μL) | 200 μL |
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| EIF2ABA-20-GRGO | 20 (40 μL) | 200 μL |
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| EIF2ABA-20-GROR | 20 (40 μL) | 200 μL |
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| EIF2ABA-20-GRRE | 20 (40 μL) | 200 μL |
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| EIF2ABA-20-REGO | 20 (40 μL) | 200 μL |
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| EIF2ABA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010]
Gene Details
Gene Symbol: EIF2S1
Gene Name: Eukaryotic Translation Initiation Factor 2 Subunit Alpha
Chromosome: CHR14: 67827033-67853233
Locus: 14q23.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: EIF2A FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: EIF2S1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping