EIF-2 FISH Probe
The EIF-2 FISH probe is designed to hybridize to the EIF-2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| EIF2S1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| EIF2S1-20-RE | 20 (40 μL) | 200 μL |  |
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| EIF2S1-20-GO | 20 (40 μL) | 200 μL |  |
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| EIF2S1-20-GR | 20 (40 μL) | 200 μL |  |
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| EIF2S1-20-AQ | 20 (40 μL) | 200 μL |  |
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| EIF2S1-20-DIG | 20 (40 μL) | 200 μL |  |
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| EIF2S1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010]
Gene Details
Gene Symbol: EIF2S1
Gene Name: Eukaryotic Translation Initiation Factor 2 Subunit Alpha
Chromosome: CHR14: 67827033-67853233
Locus: 14q23.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: EIF-2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: EIF2S1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping