EGLN1 Break Apart FISH Probe
Empire Genomics’ EGLN1 Break Apart FISH Probe is designed to flank the EGLN1 gene and is typically used for detecting EGLN1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| EGLN1BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| EGLN1BA-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| EGLN1BA-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| EGLN1BA-20-GORE | 20 (40 μL) | 200 μL |
|
|
| EGLN1BA-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| EGLN1BA-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| EGLN1BA-20-ORGR | 20 (40 μL) | 200 μL |
|
|
| EGLN1BA-20-REGO | 20 (40 μL) | 200 μL |
|
|
| EGLN1BA-20-REGR | 20 (40 μL) | 200 μL |
|
Gene Summary
The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3). [provided by RefSeq, Nov 2009]
Gene Details
Gene Symbol: EGLN1
Gene Name: Egl-9 Family Hypoxia Inducible Factor 1
Chromosome: CHR1: 231499496-231560790
Locus: 1q42.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: EGLN1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: EGLN1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping