EGLN1 FISH Probe
The EGLN1 FISH probe is designed to hybridize to the EGLN1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
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| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| EGLN1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| EGLN1-20-RE | 20 (40 μL) | 200 μL |  |
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| EGLN1-20-GO | 20 (40 μL) | 200 μL |  |
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| EGLN1-20-GR | 20 (40 μL) | 200 μL |  |
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| EGLN1-20-AQ | 20 (40 μL) | 200 μL |  |
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| EGLN1-20-DIG | 20 (40 μL) | 200 μL |  |
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| EGLN1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3). [provided by RefSeq, Nov 2009]
Gene Details
Gene Symbol: EGLN1
Gene Name: Egl-9 Family Hypoxia Inducible Factor 1
Chromosome: CHR1: 231499496-231560790
Locus: 1q42.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: EGLN1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: EGLN1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping