EGFRBP-GRB2 FISH Probe
The EGFRBP-GRB2 FISH probe is designed to hybridize to the EGFRBP-GRB2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
GRB2-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
GRB2-20-RE | 20 (40 μL) | 200 μL | ||
GRB2-20-GO | 20 (40 μL) | 200 μL | ||
GRB2-20-GR | 20 (40 μL) | 200 μL | ||
GRB2-20-AQ | 20 (40 μL) | 200 μL | ||
GRB2-20-DIG | 20 (40 μL) | 200 μL | ||
GRB2-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: GRB2
Gene Name: Growth Factor Receptor Bound Protein 2
Chromosome: CHR17: 73314156-73401790
Locus: 17q25.1
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: EGFRBP-GRB2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GRB2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping