EG627648 FISH Probe
The EG627648 FISH probe is designed to hybridize to the EG627648 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KLHL3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| KLHL3-20-RE | 20 (40 μL) | 200 μL |  |
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| KLHL3-20-GO | 20 (40 μL) | 200 μL |  |
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| KLHL3-20-GR | 20 (40 μL) | 200 μL |  |
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| KLHL3-20-AQ | 20 (40 μL) | 200 μL |  |
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| KLHL3-20-DIG | 20 (40 μL) | 200 μL |  |
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| KLHL3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene is ubiquitously expressed and encodes a full-length protein which has an N-terminal BTB domain followed by a BACK domain and six kelch-like repeats in the C-terminus. These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex. Muatations in this gene cause pseudohypoaldosteronism type IID (PHA2D); a rare Mendelian syndrome featuring hypertension, hyperkalaemia and metabolic acidosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2012]
Gene Details
Gene Symbol: KLHL3
Gene Name: Kelch Like Family Member 3
Chromosome: CHR5: 136953188-137071779
Locus: 5q31.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: EG627648 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: KLHL3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping