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EDN3 FISH Probe

The EDN3 FISH probe is designed to hybridize to the EDN3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
EDN3-20-OR  (Standard Design) 20 (40 μL) 200 μL
EDN3-20-RE 20 (40 μL) 200 μL
EDN3-20-GO 20 (40 μL) 200 μL
EDN3-20-GR 20 (40 μL) 200 μL
EDN3-20-AQ 20 (40 μL) 200 μL
EDN3-20-DIG 20 (40 μL) 200 μL
EDN3-20-BIO 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Altered expression of this gene is implicated in tumorigenesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2014]

Gene Details

Gene Symbol: EDN3

Gene Name: Endothelin 3

Chromosome: CHR20: 57875498-57901047

Locus: 20q13.32

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.

Product Details

Product: EDN3 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: EDN3-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping