EDARADD Break Apart FISH Probe
Empire Genomics’ EDARADD Break Apart FISH Probe is designed to flank the EDARADD gene and is typically used for detecting EDARADD rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
EDARADDBA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL | ||
EDARADDBA-20-AQOR | 20 (40 μL) | 200 μL | ||
EDARADDBA-20-GOGR | 20 (40 μL) | 200 μL | ||
EDARADDBA-20-GORE | 20 (40 μL) | 200 μL | ||
EDARADDBA-20-GRGO | 20 (40 μL) | 200 μL | ||
EDARADDBA-20-GROR | 20 (40 μL) | 200 μL | ||
EDARADDBA-20-GRRE | 20 (40 μL) | 200 μL | ||
EDARADDBA-20-REGO | 20 (40 μL) | 200 μL | ||
EDARADDBA-20-REGR | 20 (40 μL) | 200 μL |
Gene Summary
This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: EDARADD
Gene Name: EDAR Associated Death Domain
Chromosome: CHR1: 236557679-236648008
Locus: 1q42.3-q43
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
---|
Customer Publications
Product Details
Product: EDARADD FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: EDARADD-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping