ECTD11A FISH Probe
The ECTD11A FISH probe is designed to hybridize to the ECTD11A gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| EDARADD-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| EDARADD-20-RE | 20 (40 μL) | 200 μL |  |
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| EDARADD-20-GO | 20 (40 μL) | 200 μL |  |
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| EDARADD-20-GR | 20 (40 μL) | 200 μL |  |
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| EDARADD-20-AQ | 20 (40 μL) | 200 μL |  |
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| EDARADD-20-DIG | 20 (40 μL) | 200 μL |  |
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| EDARADD-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: EDARADD
Gene Name: EDAR Associated Death Domain
Chromosome: CHR1: 236557679-236648008
Locus: 1q42.3-q43
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ECTD11A FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: EDARADD-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping