E47 FISH Probe
The E47 FISH probe is designed to hybridize to the E47 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TCF3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TCF3-20-RE | 20 (40 μL) | 200 μL |  |
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| TCF3-20-GO | 20 (40 μL) | 200 μL |  |
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| TCF3-20-GR | 20 (40 μL) | 200 μL |  |
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| TCF3-20-AQ | 20 (40 μL) | 200 μL |  |
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| TCF3-20-DIG | 20 (40 μL) | 200 μL |  |
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| TCF3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1;19), with PBX1), childhood leukemia (t(19;19), with TFPT) and acute leukemia (t(12;19), with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, Sep 2011]
Gene Details
Gene Symbol: TCF3
Gene Name: Transcription Factor 3
Chromosome: CHR19: 1609288-1652328
Locus: 19p13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: E47 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TCF3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping