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E2F4 FISH Probe

The E2F4 FISH probe is designed to hybridize to the E2F4 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
E2F4-20-OR  (Standard Design) 20 (40 μL) 200 μL
E2F4-20-RE 20 (40 μL) 200 μL
E2F4-20-GO 20 (40 μL) 200 μL
E2F4-20-GR 20 (40 μL) 200 μL
E2F4-20-AQ 20 (40 μL) 200 μL
E2F4-20-DIG 20 (40 μL) 200 μL
E2F4-20-BIO 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein binds to all three of the tumor suppressor proteins pRB, p107 and p130, but with higher affinity to the last two. It plays an important role in the suppression of proliferation-associated genes, and its gene mutation and increased expression may be associated with human cancer. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: E2F4

Gene Name: E2F Transcription Factor 4

Chromosome: CHR16: 67226067-67232821

Locus: 16q22.1

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: E2F4 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: E2F4-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping