E25B FISH Probe
The E25B FISH probe is designed to hybridize to the E25B gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ITM2B-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ITM2B-20-RE | 20 (40 μL) | 200 μL |  |
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| ITM2B-20-GO | 20 (40 μL) | 200 μL |  |
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| ITM2B-20-GR | 20 (40 μL) | 200 μL |  |
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| ITM2B-20-AQ | 20 (40 μL) | 200 μL |  |
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| ITM2B-20-DIG | 20 (40 μL) | 200 μL |  |
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| ITM2B-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia. [provided by RefSeq, Oct 2009]
Gene Details
Gene Symbol: ITM2B
Gene Name: Integral Membrane Protein 2B
Chromosome: CHR13: 48807273-48836232
Locus: 13q14.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: E25B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ITM2B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping