E2.2 FISH Probe
The E2.2 FISH probe is designed to hybridize to the E2.2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TCF4-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TCF4-20-RE | 20 (40 μL) | 200 μL |  |
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| TCF4-20-GO | 20 (40 μL) | 200 μL |  |
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| TCF4-20-GR | 20 (40 μL) | 200 μL |  |
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| TCF4-20-AQ | 20 (40 μL) | 200 μL |  |
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| TCF4-20-DIG | 20 (40 μL) | 200 μL |  |
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| TCF4-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. In addition, an intronic CTG repeat normally numbering 10-37 repeat units can expand to >50 repeat units and cause Fuchs endothelial corneal dystrophy. Multiple alternatively spliced transcript variants that encode different proteins have been described. [provided by RefSeq, Jul 2016]
Gene Details
Gene Symbol: TCF4
Gene Name: Transcription Factor 4
Chromosome: CHR18: 52889561-53303188
Locus: 18q21.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: E2.2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TCF4-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping