E2(17)KB2 FISH Probe
The E2(17)KB2 FISH probe is designed to hybridize to the E2(17)KB2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| UBE2D2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| UBE2D2-20-RE | 20 (40 μL) | 200 μL |  |
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| UBE2D2-20-GO | 20 (40 μL) | 200 μL |  |
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| UBE2D2-20-GR | 20 (40 μL) | 200 μL |  |
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| UBE2D2-20-AQ | 20 (40 μL) | 200 μL |  |
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| UBE2D2-20-DIG | 20 (40 μL) | 200 μL |  |
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| UBE2D2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Regulated degradation of misfolded, damaged or short-lived proteins in eukaryotes occurs via the ubiquitin (Ub)-proteasome system (UPS). An integral part of the UPS system is the ubiquitination of target proteins and covalent linkage of Ub-containing proteins to form polymeric chains, marking them as targets for 26S proteasome-mediated degradation. Ubiquitination of proteins is mediated by a cascade of enzymes which includes E1 (ubiquitin activating), E2 (ubiquitin conjugating), and E3 (ubiquitin ligases) enzymes. This gene encodes a member of the E2 enzyme family. Substrates of this enzyme include the tumor suppressor protein p53 and peroxisomal biogenesis factor 5 (PEX5). Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013]
Gene Details
Gene Symbol: UBE2D2
Gene Name: Ubiquitin Conjugating Enzyme E2 D2
Chromosome: CHR5: 138940750-139008018
Locus: 5q31.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: E2(17)KB2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: UBE2D2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping