E2(17)KB1 FISH Probe
The E2(17)KB1 FISH probe is designed to hybridize to the E2(17)KB1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| UBE2D1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| UBE2D1-20-RE | 20 (40 μL) | 200 μL |  |
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| UBE2D1-20-GO | 20 (40 μL) | 200 μL |  |
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| UBE2D1-20-GR | 20 (40 μL) | 200 μL |  |
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| UBE2D1-20-AQ | 20 (40 μL) | 200 μL |  |
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| UBE2D1-20-DIG | 20 (40 μL) | 200 μL |  |
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| UBE2D1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
Gene Details
Gene Symbol: UBE2D1
Gene Name: Ubiquitin Conjugating Enzyme E2 D1
Chromosome: CHR10: 60094738-60130513
Locus: 10q21.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: E2(17)KB1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: UBE2D1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping