E170 FISH Probe
The E170 FISH probe is designed to hybridize to the E170 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LAMA3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| LAMA3-20-RE | 20 (40 μL) | 200 μL |  |
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| LAMA3-20-GO | 20 (40 μL) | 200 μL |  |
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| LAMA3-20-GR | 20 (40 μL) | 200 μL |  |
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| LAMA3-20-AQ | 20 (40 μL) | 200 μL |  |
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| LAMA3-20-DIG | 20 (40 μL) | 200 μL |  |
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| LAMA3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene belongs to the laminin family of secreted molecules. Laminins are heterotrimeric molecules that consist of alpha, beta, and gamma subunits that assemble through a coiled-coil domain. Laminins are essential for formation and function of the basement membrane and have additional functions in regulating cell migration and mechanical signal transduction. This gene encodes an alpha subunit and is responsive to several epithelial-mesenchymal regulators including keratinocyte growth factor, epidermal growth factor and insulin-like growth factor. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa and laryngoonychocutaneous syndrome. Alternative splicing and alternative promoter usage result in multiple transcript variants. [provided by RefSeq, Dec 2014]
Gene Details
Gene Symbol: LAMA3
Gene Name: Laminin Subunit Alpha 3
Chromosome: CHR18: 21269561-21535029
Locus: 18q11.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: E170 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: LAMA3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping