DYRK1A Break Apart FISH Probe
Empire Genomics’ DYRK1A Break Apart FISH Probe is designed to flank the DYRK1A gene and is typically used for detecting DYRK1A rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DYRK1ABA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DYRK1ABA-20-AQOR | 20 (40 μL) | 200 μL |
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| DYRK1ABA-20-GOGR | 20 (40 μL) | 200 μL |
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| DYRK1ABA-20-GORE | 20 (40 μL) | 200 μL |
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| DYRK1ABA-20-GRGO | 20 (40 μL) | 200 μL |
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| DYRK1ABA-20-GROR | 20 (40 μL) | 200 μL |
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| DYRK1ABA-20-GRRE | 20 (40 μL) | 200 μL |
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| DYRK1ABA-20-REGO | 20 (40 μL) | 200 μL |
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| DYRK1ABA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome. Alternative splicing of this gene generates several transcript variants differing from each other either in the 5' UTR or in the 3' coding region. These variants encode at least five different isoforms. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: DYRK1A
Gene Name: Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A
Chromosome: CHR21: 38739858-38887679
Locus: 21q22.13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DYRK1A FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DYRK1A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping