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DUSP6 FISH Probe

The DUSP6 FISH probe is designed to hybridize to the DUSP6 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
DUSP6-20-OR  (Standard Design) 20 (40 μL) 200 μL
DUSP6-20-RE 20 (40 μL) 200 μL
DUSP6-20-GO 20 (40 μL) 200 μL
DUSP6-20-GR 20 (40 μL) 200 μL
DUSP6-20-AQ 20 (40 μL) 200 μL
DUSP6-20-DIG 20 (40 μL) 200 μL
DUSP6-20-BIO 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Mutations in this gene have been associated with congenital hypogonadotropic hypogonadism. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2014]

Gene Details

Gene Symbol: DUSP6

Gene Name: Dual Specificity Phosphatase 6

Chromosome: CHR12: 89741836-89746296

Locus: 12q21.33

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.

Product Details

Product: DUSP6 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: DUSP6-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping