DUBA FISH Probe
The DUBA FISH probe is designed to hybridize to the DUBA gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| OTUD5-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| OTUD5-20-RE | 20 (40 μL) | 200 μL |  |
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| OTUD5-20-GO | 20 (40 μL) | 200 μL |  |
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| OTUD5-20-GR | 20 (40 μL) | 200 μL |  |
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| OTUD5-20-AQ | 20 (40 μL) | 200 μL |  |
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| OTUD5-20-DIG | 20 (40 μL) | 200 μL |  |
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| OTUD5-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Oct 2008]
Gene Details
Gene Symbol: OTUD5
Gene Name: OTU Deubiquitinase 5
Chromosome: CHRX: 48779302-48815648
Locus: Xp11.23
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DUBA FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: OTUD5-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping