DSG-1 FISH Probe
The DSG-1 FISH probe is designed to hybridize to the DSG-1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DSG1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| DSG1-20-RE | 20 (40 μL) | 200 μL |  |
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| DSG1-20-GO | 20 (40 μL) | 200 μL |  |
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| DSG1-20-GR | 20 (40 μL) | 200 μL |  |
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| DSG1-20-AQ | 20 (40 μL) | 200 μL |  |
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| DSG1-20-DIG | 20 (40 μL) | 200 μL |  |
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| DSG1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma. [provided by RefSeq, Feb 2015]
Gene Details
Gene Symbol: DSG1
Gene Name: Desmoglein 1
Chromosome: CHR18: 28898051-28937393
Locus: 18q12.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DSG-1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DSG1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping