DR1 FISH Probe
The DR1 FISH probe is designed to hybridize to the DR1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DR1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| DR1-20-RE | 20 (40 μL) | 200 μL |  |
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| DR1-20-GO | 20 (40 μL) | 200 μL |  |
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| DR1-20-GR | 20 (40 μL) | 200 μL |  |
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| DR1-20-AQ | 20 (40 μL) | 200 μL |  |
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| DR1-20-DIG | 20 (40 μL) | 200 μL |  |
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| DR1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: DR1
Gene Name: Down-regulator Of Transcription 1
Chromosome: CHR1: 93811477-93828148
Locus: 1p22.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DR1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DR1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping