DOBI FISH Probe
The DOBI FISH probe is designed to hybridize to the DOBI gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PUS10-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PUS10-20-RE | 20 (40 μL) | 200 μL |  |
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| PUS10-20-GO | 20 (40 μL) | 200 μL |  |
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| PUS10-20-GR | 20 (40 μL) | 200 μL |  |
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| PUS10-20-AQ | 20 (40 μL) | 200 μL |  |
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| PUS10-20-DIG | 20 (40 μL) | 200 μL |  |
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| PUS10-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Pseudouridination, the isomerization of uridine to pseudouridine, is the most common posttranscriptional nucleotide modification found in RNA and is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate synthases, such as PUS10, catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. These enzymes also act as RNA chaperones, facilitating the correct folding and assembly of tRNAs (McCleverty et al., 2007 [PubMed 17900615]).[supplied by OMIM, May 2009]
Gene Details
Gene Symbol: PUS10
Gene Name: Pseudouridylate Synthase 10
Chromosome: CHR2: 61167547-61245365
Locus: 2p16.1-p15
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: DOBI FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PUS10-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping