DMGDHD FISH Probe
The DMGDHD FISH probe is designed to hybridize to the DMGDHD gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DMGDH-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| DMGDH-20-RE | 20 (40 μL) | 200 μL |  |
|
| DMGDH-20-GO | 20 (40 μL) | 200 μL |  |
|
| DMGDH-20-GR | 20 (40 μL) | 200 μL |  |
|
| DMGDH-20-AQ | 20 (40 μL) | 200 μL |  |
|
| DMGDH-20-DIG | 20 (40 μL) | 200 μL |  |
|
| DMGDH-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. Mutation in this gene causes dimethylglycine dehydrogenase deficiency, characterized by a fishlike body odor, chronic muscle fatigue, and elevated levels of the muscle form of creatine kinase in serum. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Gene Details
Gene Symbol: DMGDH
Gene Name: Dimethylglycine Dehydrogenase
Chromosome: CHR5: 78293428-78365449
Locus: 5q14.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: DMGDHD FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DMGDH-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping