DMBT1 Break Apart FISH Probe
Empire Genomics’ DMBT1 Break Apart FISH Probe is designed to flank the DMBT1 gene and is typically used for detecting DMBT1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DMBT1BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DMBT1BA-20-AQOR | 20 (40 μL) | 200 μL |
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| DMBT1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| DMBT1BA-20-GORE | 20 (40 μL) | 200 μL |
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| DMBT1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| DMBT1BA-20-GROR | 20 (40 μL) | 200 μL |
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| DMBT1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| DMBT1BA-20-REGO | 20 (40 μL) | 200 μL |
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| DMBT1BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. This gene was originally isolated based on its deletion in a medulloblastoma cell line. This gene is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized. The encoded protein precursor is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition. This indicates that DMBT1 may not be a classical tumor suppressor gene, but rather play a role in the interaction of tumor cells and the immune system. [provided by RefSeq, Mar 2016]
Gene Details
Gene Symbol: DMBT1
Gene Name: Deleted In Malignant Brain Tumors 1
Chromosome: CHR10: 124320180-124403252
Locus: 10q26.13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DMBT1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DMBT1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping