DKCB3 FISH Probe
The DKCB3 FISH probe is designed to hybridize to the DKCB3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| WRAP53-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| WRAP53-20-RE | 20 (40 μL) | 200 μL |  |
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| WRAP53-20-GO | 20 (40 μL) | 200 μL |  |
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| WRAP53-20-GR | 20 (40 μL) | 200 μL |  |
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| WRAP53-20-AQ | 20 (40 μL) | 200 μL |  |
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| WRAP53-20-DIG | 20 (40 μL) | 200 μL |  |
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| WRAP53-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes an essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex required for telomere synthesis. This protein is enriched in Cajal bodies, nuclear sites of RNP processing that are important for telomerase function. It interacts with dyskerin, TERT and TERC, other components of active telomerase, and with small Cajal body RNAs (scaRNAs), which are involved in modifying splicing RNAs. This mRNA also functions as a p53 antisense transcript, that regulates endogenous p53 mRNA levels and further induction of p53 protein by targeting the 5' untranslated region of p53 mRNA. Alternatively spliced transcript variants which differ only in the 5' UTR have been found for this gene. [provided by RefSeq, Mar 2011]
Gene Details
Gene Symbol: WRAP53
Gene Name: WD Repeat Containing Antisense To TP53
Chromosome: CHR17: 7589388-7606820
Locus: 17p13.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DKCB3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: WRAP53-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping