DKC1 Break Apart FISH Probe
Empire Genomics’ DKC1 Break Apart FISH Probe is designed to flank the DKC1 gene and is typically used for detecting DKC1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DKC1BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DKC1BA-20-AQOR | 20 (40 μL) | 200 μL |
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| DKC1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| DKC1BA-20-GORE | 20 (40 μL) | 200 μL |
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| DKC1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| DKC1BA-20-GROR | 20 (40 μL) | 200 μL |
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| DKC1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| DKC1BA-20-REGO | 20 (40 μL) | 200 μL |
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| DKC1BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Gene Details
Gene Symbol: DKC1
Gene Name: Dyskerin Pseudouridine Synthase 1
Chromosome: CHRX: 153991030-154005964
Locus: Xq28
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DKC1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DKC1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping