DHP FISH Probe
The DHP FISH probe is designed to hybridize to the DHP gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DPYD-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| DPYD-20-RE | 20 (40 μL) | 200 μL |  |
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| DPYD-20-GO | 20 (40 μL) | 200 μL |  |
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| DPYD-20-GR | 20 (40 μL) | 200 μL |  |
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| DPYD-20-AQ | 20 (40 μL) | 200 μL |  |
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| DPYD-20-DIG | 20 (40 μL) | 200 μL |  |
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| DPYD-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
Gene Details
Gene Symbol: DPYD
Gene Name: Dihydropyrimidine Dehydrogenase
Chromosome: CHR1: 97543299-98386615
Locus: 1p21.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DHP FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DPYD-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping