DHFR FISH Probe
The DHFR FISH probe is designed to hybridize to the DHFR gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DHFR-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| DHFR-20-RE | 20 (40 μL) | 200 μL |  |
|
| DHFR-20-GO | 20 (40 μL) | 200 μL |  |
|
| DHFR-20-GR | 20 (40 μL) | 200 μL |  |
|
| DHFR-20-AQ | 20 (40 μL) | 200 μL |  |
|
| DHFR-20-DIG | 20 (40 μL) | 200 μL |  |
|
| DHFR-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2014]
Gene Details
Gene Symbol: DHFR
Gene Name: Dihydrofolate Reductase
Chromosome: CHR5: 79922044-79950800
Locus: 5q14.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: DHFR FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DHFR-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping