DHE3 FISH Probe
The DHE3 FISH probe is designed to hybridize to the DHE3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GLUD1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| GLUD1-20-RE | 20 (40 μL) | 200 μL |  |
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| GLUD1-20-GO | 20 (40 μL) | 200 μL |  |
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| GLUD1-20-GR | 20 (40 μL) | 200 μL |  |
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| GLUD1-20-AQ | 20 (40 μL) | 200 μL |  |
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| GLUD1-20-DIG | 20 (40 μL) | 200 μL |  |
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| GLUD1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X. [provided by RefSeq, Jan 2016]
Gene Details
Gene Symbol: GLUD1
Gene Name: Glutamate Dehydrogenase 1
Chromosome: CHR10: 88809958-88854776
Locus: 10q23.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DHE3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GLUD1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping