DFNB61 FISH Probe
The DFNB61 FISH probe is designed to hybridize to the DFNB61 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SLC26A5-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| SLC26A5-20-RE | 20 (40 μL) | 200 μL |  |
|
| SLC26A5-20-GO | 20 (40 μL) | 200 μL |  |
|
| SLC26A5-20-GR | 20 (40 μL) | 200 μL |  |
|
| SLC26A5-20-AQ | 20 (40 μL) | 200 μL |  |
|
| SLC26A5-20-DIG | 20 (40 μL) | 200 μL |  |
|
| SLC26A5-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the SLC26A/SulP transporter family. The protein functions as a molecular motor in motile outer hair cells (OHCs) of the cochlea, inducing changes in cell length that act to amplify sound levels. The transmembrane protein is an incomplete anion transporter, and does not allow anions to cross the cell membrane but instead undergoes a conformational change in response to changes in intracellular Cl- levels that results in a change in cell length. The protein functions at microsecond rates, which is several orders of magnitude faster than conventional molecular motor proteins. Mutations in this gene are potential candidates for causing neurosensory deafness. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2009]
Gene Details
Gene Symbol: SLC26A5
Gene Name: Solute Carrier Family 26 Member 5
Chromosome: CHR7: 102993176-103086624
Locus: 7q22.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: DFNB61 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SLC26A5-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping