DFNB3 FISH Probe
The DFNB3 FISH probe is designed to hybridize to the DFNB3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MYO15A-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MYO15A-20-RE | 20 (40 μL) | 200 μL |  |
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| MYO15A-20-GO | 20 (40 μL) | 200 μL |  |
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| MYO15A-20-GR | 20 (40 μL) | 200 μL |  |
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| MYO15A-20-AQ | 20 (40 μL) | 200 μL |  |
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| MYO15A-20-DIG | 20 (40 μL) | 200 μL |  |
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| MYO15A-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes an unconventional myosin. This protein differs from other myosins in that it has a long N-terminal extension preceding the conserved motor domain. Studies in mice suggest that this protein is necessary for actin organization in the hair cells of the cochlea. Mutations in this gene have been associated with profound, congenital, neurosensory, nonsyndromal deafness. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Read-through transcripts containing an upstream gene and this gene have been identified, but they are not thought to encode a fusion protein. Several alternatively spliced transcript variants have been described, but their full length sequences have not been determined. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: MYO15A
Gene Name: Myosin XVA
Chromosome: CHR17: 18012019-18083116
Locus: 17p11.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DFNB3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MYO15A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping