DFNA70 FISH Probe
The DFNA70 FISH probe is designed to hybridize to the DFNA70 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MCM2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MCM2-20-RE | 20 (40 μL) | 200 μL |  |
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| MCM2-20-GO | 20 (40 μL) | 200 μL |  |
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| MCM2-20-GR | 20 (40 μL) | 200 μL |  |
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| MCM2-20-AQ | 20 (40 μL) | 200 μL |  |
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| MCM2-20-DIG | 20 (40 μL) | 200 μL |  |
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| MCM2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Oct 2012]
Gene Details
Gene Symbol: MCM2
Gene Name: Minichromosome Maintenance Complex Component 2
Chromosome: CHR3: 127317252-127341278
Locus: 3q21.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DFNA70 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MCM2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping