DFH FISH Probe
The DFH FISH probe is designed to hybridize to the DFH gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
FH-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
FH-20-RE | 20 (40 μL) | 200 μL | ||
FH-20-GO | 20 (40 μL) | 200 μL | ||
FH-20-GR | 20 (40 μL) | 200 μL | ||
FH-20-AQ | 20 (40 μL) | 200 μL | ||
FH-20-DIG | 20 (40 μL) | 200 μL | ||
FH-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: FH
Gene Name: Fumarate Hydratase
Chromosome: CHR1: 241660856-241683085
Locus: 1q43
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DFH FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: FH-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping