DFFB Break Apart FISH Probe
Empire Genomics’ DFFB Break Apart FISH Probe is designed to flank the DFFB gene and is typically used for detecting DFFB rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DFFBBA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DFFBBA-20-AQOR | 20 (40 μL) | 200 μL |
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| DFFBBA-20-GOGR | 20 (40 μL) | 200 μL |
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| DFFBBA-20-GORE | 20 (40 μL) | 200 μL |
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| DFFBBA-20-GRGO | 20 (40 μL) | 200 μL |
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| DFFBBA-20-GROR | 20 (40 μL) | 200 μL |
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| DFFBBA-20-GRRE | 20 (40 μL) | 200 μL |
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| DFFBBA-20-REGO | 20 (40 μL) | 200 μL |
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| DFFBBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene but the biological validity of some of these variants has not been determined. [provided by RefSeq, Sep 2013]
Gene Details
Gene Symbol: DFFB
Gene Name: DNA Fragmentation Factor Subunit Beta
Chromosome: CHR1: 3773844-3801993
Locus: 1p36.32
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DFFB FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DFFB-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping